I tredje sæson af Gossip girl følger man fortsat de unge og rige fra en eksklusiv privatskole i New Yorks Upper East side, og alle de intrige, som de roder sig ud i.
DVD boksen indeholder følgende afsnit:
Disc 1: Reversals of fortune, The Freshman, The lost boy, Dan de fleurette, Rufus getting married.
Disc 2: Enough about Eve, How to succeed in Bassness, The grandfather: part 2, They shoot Humpfreys don´t they, The last days of disco.
Disc 3: The treasure of serena madre, The debarted, The hurt locket, The lady vanished, The sixteen year old virgin.
Disc 4: The empire strikes jack, Inglorius bassterds, The unblairable lightness of being, Gossip girl mode.
Disc 5: Dr. estrangeloved, It's a dad, dad, dad, dad world, Ex-husbands and wifes, Last tango, then Paris.